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[Establishment of Chinese hamster ovary cell line expressing recombinant GPIb-IX complex].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2009

Liao Yi, Zhang Wei-Lin, Yuan Yan-Hong, Shi Quan-Wei, Li Su-Ping, Yan Rong, Wang Zhi-Cheng, Dai Ke-Sheng

Abstract excerpt

The aim of this study was to construct Chinese Hamster Ovary (CHO) cell models expressing recombinant wild-type GPIb-IX and mutant GPIb-IX complex, so as to provide the platform to study the related physiologic functions of GPIb-IX. The plasmids were extracted from E.coli expressing wild-type or deletion mutant GPIbalpha and were identified by digestion with EcoR I. Three plasmids containing GPIbalpha, GPIbbeta,...

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PMID: 20030947

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