Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of molecular defect of 13387-9delG mutated antithrombin in inherited type I antithrombin deficiency.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 2005

Wang Wen-Bin, Fu Qi-Hua, Ding Qiu-Lan, Zhou Rong-Fu, Wu Wen-Man, Hu Yi-Qun, Wang Xue-Feng, Yan Li-Xing, Wang Zhen-Yi, Wang Hong-Li

Abstract excerpt

As a major physiological inhibitor of thrombin and other coagulation proteases, antithrombin (AT) plays an important role in the maintenance of normal hemostasis and its deficiency is associated with a predisposition for familial venous thromboembolic disease. Recently, we found a novel mutation (13387-9delG) in the antithrombin gene that is associated with type I AT deficiency. To examine the molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Antithrombin III

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antithrombin III Deficiency

Share to Chlorocebus aethiops

Share to CHO Cells

Share to COS Cells

Share to Cricetinae

Share to Gene Expression

Source

Identifiers

PMID: 15741804
DOI: 10.1097/01.mbc.0000161570.04883.25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of molecular defect of 13387-9delG mutated antithrombin in inherited type I antithrombin deficiency.PMID 15741804Read ↗

Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations.Semantic proximity Read ↗

Molecular basis of type I antithrombin deficiency in two women with recurrent venous thromboembolism in the first trimester of pregnancy.Semantic proximity Read ↗

Identification of a novel amino acid deletion mutation and a very rare single nucleotide variant in a Japanese family with type I antithrombin deficiency.Semantic proximity Read ↗

Molecular mechanisms of antithrombin deficiency in two Chinese families. One novel and one recurrent point mutation in the antithrombin gene causing venous thrombosis.Semantic proximity Read ↗

Two novel gene mutations in type I antithrombin deficiency.Semantic proximity Read ↗

Molecular basis of inherited human antithrombin deficiency.Semantic proximity Read ↗

Characterization of two novel mutations of the antithrombin gene observed in Japanese thrombophilic patients.Semantic proximity Read ↗

[A novel mutation in antithrombin gene results in hereditary antithrombin deficiency].Semantic proximity Read ↗

[Molecular mechanisms of antithrombin deficiency caused by novel double heterozygous mutations].Semantic proximity Read ↗

An overview of the mechanism of action of antithrombin and its inherited deficiency states.Semantic proximity Read ↗

Molecular genetics of human antithrombin deficiency.Semantic proximity Read ↗

Familial variant of antithrombin III (AT III Bligny, 47Arg to His) associated with protein C deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.