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Article

Immobilization-based isolation of capsule-negative mutants of Streptococcus pneumoniae.

Microbiology (Reading, England) - 1 Jun 2005

Llull Daniel, Veiga Patrick, Tremblay Josselyne, Kulakauskas Saulius

Abstract excerpt

The capsular polysaccharide (CPS) is the most important identified virulence factor of Streptococcus pneumoniae, a human pathogen of the upper respiratory tract. One limitation in studies of S. pneumoniae surface virulence factors is the lack of a reliable procedure for isolation of capsule-negative mutants of clinical strains. This paper presents an approach, based on the immobilization of pneumococci in...

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Identifiers

PMID: 15941998
DOI: 10.1099/mic.0.27862-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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