Article
Interleukin 12 (IL12B), interleukin 12 receptor (IL12RB1) and interleukin 23 (IL23A) gene polymorphism in systemic lupus erythematosus.
Rheumatology (Oxford, England) - 1 Sept 2005
Sánchez E, Morales S, Paco L, López-Nevot M A, Hidalgo C, Jiménez-Alonso J, Torres B, González-Gay M A, Callejas J L, Ortego-Centeno N, Sánchez-Roman J, González-Escribano M F, Martín J
Abstract excerpt
OBJECTIVE: The aim of this study was to assess the possible association between the interleukin-12B (IL12B) and interleukin-12 receptor beta 1 (IL12RB1) gene polymorphisms with systemic lupus erythematosus (SLE). In addition, we have undertaken a systematic search for genetic variants of interleukin 23 (IL23A). METHODS: The study was conducted on 559 SLE patients and 603 ethnically matched healthy controls....
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