Article
Denaturing high-performance liquid chromatography technique platform applied to screen G6PD deficient variants.
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2005
Jiang Wei-ying, Chen Lu-ming, Lin Qun-di, Geng Qian, Du Chuan-shu
Abstract excerpt
OBJECTIVE: Of denaturing high performance liquid chromatography (DHPLC), a technique platform was developed for screening G6PD deficient variants. METHODS: When applied to screen and identify the G6PD deficient variants from 124 patients who come from 11 nations in China, the DHPLC was compared with amplification refractory mutation system (ARMS) or DNA sequence technique and assessed carefully in its accuracy,...
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