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Article

Folate-related genes and omphalocele.

American journal of medical genetics. Part A - 1 Jul 2005

Mills James L, Druschel Charlotte M, Pangilinan Faith, Pass Kenneth, Cox Christopher, Seltzer Rebecca R, Conley Mary R, Brody Lawrence C

Abstract excerpt

Women who take folic acid in the periconceptional period greatly reduce their chances of having a child with a neural tube defect (NTD). Using multivitamins may also reduce the risk of having a child with an omphalocele. In this study, we tested single nucleotide polymorphisms in folate-related enzyme genes for association with omphalocele. Polymorphisms in methylenetetrahydrofolate reductase (MTHFR),...

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Source

Identifiers

PMID: 15937947
DOI: 10.1002/ajmg.a.30772

Genes

MTHFR
MTHFD1
TCN2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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