Article
VEGF polymorphisms and severity of atherosclerosis.
Journal of medical genetics - 1 Jun 2005
Howell W M, Ali S, Rose-Zerilli M J, Ye S
Abstract excerpt
INTRODUCTION: Vascular endothelial growth factor (VEGF) is a potent angiogenic factor, and neovascularisation has been shown to be important in atherosclerotic plaque development. There is some disagreement as to whether VEGF acts as a pro-atherosclerotic or anti-atherosclerotic factor. In the present study we have sought to clarify this by determining genotypes and haplotypes for three reportedly functional VEGF...
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