Article
Effects of alcohol on hemodynamic and cardiovascular reaction in different genotypes.
Psychiatry research - 30 May 2005
Obata Akiko, Morimoto Kanehisa, Sato Hiroki, Takeshita Tatsuya, Kawaguchi Hideo, Koizumi Hideaki, Maki Atsushi
Abstract excerpt
This study assessed hemodynamic changes associated with alcohol intake in people who have different sensitivities to alcohol due to an inactive form of mitochondrial aldehyde dehydrogenase (ALDH). People with ALDH2*1/*2 are more sensitive to alcohol than people with ALDH2*1/*1. Six ALDH2*1/*1 subjects and four ALDH2*1/*2 subjects participated in this study. The subjects drank whisky with water (0.4 ml/kg of...
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