Article
Whole-genome screening for susceptibility genes in multicase families with Behçet's disease.
Arthritis and rheumatism - 1 Jun 2005
Karasneh Jumana, Gül Ahmet, Ollier William E, Silman Alan J, Worthington Jane
Abstract excerpt
OBJECTIVE: Behçet's disease is generally considered to be a multifactorial disease with important genetic and environmental components. A strong association between an HLA class I antigen, HLA-B51, and Behçet's disease has long been known. However, analysis of multicase families has suggested a substantial contribution of non-HLA loci. The aim of this study was to perform a whole-genome linkage analysis for...
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