Article
Differential activation of dendritic cells by Mycobacterium tuberculosis Beijing genotype.
Immunological investigations - 1 Jan 2014
Reyes-Martínez Juana Elizabeth, Nieto-Patlán Erik, Nieto-Patlán Alejandro, Gonzaga-Bernachi Job, Santos-Mendoza Teresa, Serafín-López Jeanet, Chávez-Blanco Alma, Sandoval-Montes Claudia, Flores-Romo Leopoldo, Estrada-Parra Sergio, Estrada-García Iris, Chacón-Salinas Rommel
Abstract excerpt
Mycobacterium tuberculosis (Mtb) inhibits dendritric cells (DC) function in order to delay T cell response. Furthermore, there is increasing evidence that genetic diversity of Mtb strains can affect their interaction with the immune system. Beijing genotype has attracted attention because of its high prevalence and multi-drug resistance. Although it is known that this genotype is hypervirulent and differentially...
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