Article
Mycobacterium tuberculosis Beijing genotype induces differential cytokine production by peripheral blood mononuclear cells of healthy BCG vaccinated individuals.
Immunological investigations - 1 Jan 2012
Rivera-Ordaz Araceli, Gonzaga-Bernachi Job, Serafín-López Jeanet, Hernández-Pando Rogelio, Van Soolingen Dick, Estrada-Parra Sergio, Estrada-García Iris, Chacón-Salinas Rommel
Abstract excerpt
Members of the Mycobacterium tuberculosis (Mtb) Beijing genotype are a major concern due to their high prevalence in tuberculosis patients and their high rate of multi-drug resistance. Although it has been shown that Beijing modifies macrophage behavior, little is known about how this genotype could affect the cellular immune response. In order to address this issue, peripheral blood mononuclear cells (PBMC) from...
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