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Article

DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 2005

Iwamoto Kazuya, Bundo Miki, Yamada Kazuo, Takao Hitomi, Iwayama-Shigeno Yoshimi, Yoshikawa Takeo, Kato Tadafumi

Abstract excerpt

Downregulation of oligodendrocyte-related genes, referred to as oligodendrocyte dysfunction, in schizophrenia has been revealed by DNA microarray studies. Because oligodendrocyte-specific transcription factors regulate the differentiation of oligodendrocytes, genes encoding them are prime candidates for oligodendrocyte dysfunction in schizophrenia. We found that the cytosine-guanine dinucleotide (CpG) island of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15930386
DOI: 10.1523/JNEUROSCI.0766-05.2005
PMCID: PMC6725011

Genes

SOX10
OLIG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia.PMID 15930386Read ↗

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SOX10 Expression Levels may be a Critical Mediator of White Matter Dysfunction in SchizophreniaSemantic proximity Read ↗

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