Article
The Klebsiella pneumoniae wabG gene: role in biosynthesis of the core lipopolysaccharide and virulence.
Journal of bacteriology - 1 Dec 2003
Izquierdo Luis, Coderch Núria, Piqué Nuria, Bedini Emiliano, Corsaro Maria Michela, Merino Susana, Fresno Sandra, Tomás Juan M, Regué Miguel
Abstract excerpt
To determine the function of the wabG gene in the biosynthesis of the core lipopolysaccharide (LPS) of Klebsiella pneumoniae, we constructed wabG nonpolar mutants. Data obtained from the comparative chemical and structural analysis of LPS samples obtained from the wild type, the mutant strain, an...
Topics
- Animals
- Bacterial Proteins
- Female
- Genetic Complementation Test
- Klebsiella Infections
- Klebsiella pneumoniae
- Lethal Dose 50
- Lipopolysaccharides
- Mice
- Mice, Inbred ICR
- Mutation
- Phenotype
- Pneumonia, Bacterial
- Rats
- Urinary Tract Infections