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Monitoring of circulating tumour-associated DNA as a prognostic tool for oral squamous cell carcinoma

31 May 2005

Abstract excerpt

Frequent allelic imbalances (AIs) including loss of heterozygosity and microsatellite instability on a specific chromosomal region have been identified in a variety of human malignancies. The objective of our study was to assess the possibility of prognostication and monitoring of oral squamous cell carcinoma (SCC) by microsatellite blood assay. DNA from normal and tumorous tissues and serum DNA obtained at three...

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PMID: 15928666
DOI: 10.1038/sj.bjc.6602635

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