Article
The TPH intron 7 A218C polymorphism and TCI dimension scores in alcohol-dependent patients: hints to nonspecific psychopathology.
Addictive behaviors - 1 Jul 2005
Anghelescu Ion, Klawe Christoph, Fehr Christoph, Singer Peter, Schleicher Alexandra, Himmerich Hubertus, Hiemke Christoph, Dahmen Norbert, Szegedi Armin
Abstract excerpt
AIMS: A linkage of certain alleles of the tryptophan hydroxylase (TPH) intron 7 A218C polymorphism to suicidality and antisocial behaviour has been described. The aim of our study was to find any association between dimensions of the Temperament and Character Inventory (TCI) indicating impulsivity and the TPH polymorphism alleles in unselected alcohol-dependent patients and age-matched controls. METHODS: We...
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