Article
Adiponectin gene variation associates with the increasing risk of type 2 diabetes in non-diabetic Japanese subjects.
International journal of molecular medicine - 1 Jan 2005
Nakatani Kaname, Noma Katsura, Nishioka Junji, Kasai Yasunari, Morioka Kohei, Katsuki Akira, Hori Yasuko, Yano Yutaka, Sumida Yasuhiro, Wada Hideo, Nobori Tsutomu
Abstract excerpt
Adiponectin is an adipocyte-secreted protein that is known to modulate insulin sensitivity and glucose homeostasis. A number of genetic variations have been studied. Among them, two single-nucleotide polymorphisms (SNP45T>G, SNP276G>T) showed an association with type 2 diabetes in the Japanese population. In this study, we examined the association between these SNPs and risk factors of type 2 diabetes in 194...
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