Article
Long‐Term Maintenance of Hematopoietic Stem Cells Does Not Require Contact with Embryo‐Derived Stromal Cells in Cocultures
25 May 2005
Abstract excerpt
We recently established that two midgestation-derived stromal clones--UG26-1B6, urogenital ridge-derived, and EL08-1D2, embryonic liver-derived--support the maintenance of murine adult bone marrow and human cord blood hematopoietic repopulating stem cells (HSCs). In this study, we investigate whether direct HSC-stroma contact is required for this stem cell maintenance. Adult bone marrow ckit+ Ly-6C- side...
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