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Article

Germline bottlenecks, biparental inheritance and selection on mitochondrial variants: a two-level selection model.

Genetics - 1 Jul 2005

Roze Denis, Rousset François, Michalakis Yannis

Abstract excerpt

Selection on mitochondrial mutations potentially occurs at different levels: at the mitochondria, cell, and organism levels. Several factors affect the strength of selection at these different levels; in particular, mitochondrial bottlenecks during germline development and reduced paternal transmission decrease the genetic variance within cells, while they increase the variance between cells and between...

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Identifiers

PMID: 15911581
DOI: 10.1534/genetics.104.039495
PMCID: PMC1451199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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