Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the TSHR (thyrotropin receptor) gene on chromosome 14q31 are not associated with mental retardation in the iodine-deficient areas of China.

Neuroscience letters - 1 Jan 2000

Guo Ting-Wei, Zhang Fu-Chang, Gao Jian-Jun, Bian Li, Gao Xiao-cai, Ma Jie, Yang Maosheng, Ji Qian, Duan Shi-wei, Zheng Zi-jian, Li Rui-lin, Feng Guo-yin, St Clair David, He Lin

Abstract excerpt

Mental retardation (MR) is one of the most frequent handicaps among children. Fetal iodine deficiency disorder (FIDD) is the commonest cause of preventable MR. However, not everyone in the iodine-deficient areas is affected and familial aggregation is common. This suggests that genetic factors ma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Chromosomes, Human, Pair 14

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Congenital Hypothyroidism

Share to Gene Frequency

Share to Iodine

Share to Linkage Disequilibrium

Share to Receptors, Thyrotropin

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 15911145
DOI: 10.1016/j.neulet.2005.03.007

Genes

TSHR
DIO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15911145-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the TSHR (thyrotropin receptor) gene on chromosome 14q31 are not associated with mental retardation in the iodine-deficient areas of China.PMID 15911145Read ↗

Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China.Semantic proximity Read ↗

An association study between the transthyretin (TTR) gene and mental retardation.Semantic proximity Read ↗

An association study of the SLC26A4 gene in children with mental retardation.Semantic proximity Read ↗

A family-based association study of DIO2 and children mental retardation in the Qinba region of China.Semantic proximity Read ↗

Apolipoprotein E is a genetic risk factor for fetal iodine deficiency disorder in China.Semantic proximity Read ↗

Association between ε2/3/4, promoter polymorphism (-491A/T, -427T/C, and -219T/G) at the apolipoprotein E gene, and mental retardation in children from an iodine deficiency area, China.Semantic proximity Read ↗

Association of TSHR gene single nucleotide intronic polymorphism with the risk of hypothyroid and hyperthyroid disorders in Yazd province.Semantic proximity Read ↗

Positive association between POU1F1 and mental retardation in young females in the Chinese Han population.Semantic proximity Read ↗

Effect of DIO2 Gene Polymorphism on Thyroid Hormone Levels and Its Correlation with the Severity of Schizophrenia in a Pakistani Population.Semantic proximity Read ↗

Variants in the RAB3A gene are not associated with mental retardation in the Chinese population.Semantic proximity Read ↗

Genetics and phenomics of hypothyroidism and goiter due to iodotyrosine deiodinase (DEHAL1) gene mutations.Semantic proximity Read ↗

Genetic factors that might lead to different responses in individuals exposed to perchlorate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.