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Article

Apolipoprotein E is a genetic risk factor for fetal iodine deficiency disorder in China.

Molecular psychiatry - 1 Jul 2000

Wang H Y, Zhang F C, Gao J J, Fan J B, Liu P, Zheng Z J, Xi H, Sun Y, Gao X C, Huang T Z, Ke Z J, Guo G R, Feng G Y, Breen G, Clair D S, He L

Abstract excerpt

Fetal iodine deficiency disorder (FIDD) is the principal form of endemic cretinism, and the most common cause of preventable mental deficiency in the world. However not everyone at risk develops FIDD and familial aggregation is common. This suggests that genetic factors may also be involved. The Apolipoprotein E (APOE) gene encodes for a lipoprotein that possesses a thyroid hormone binding domain, and APOE...

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Source

Identifiers

PMID: 10889546
DOI: 10.1038/sj.mp.4000735

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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