Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The gene encoding the alpha1A-voltage-dependent calcium channel (CACN1A4) is not a candidate for causing common subtypes of idiopathic generalized epilepsy.

Epilepsy research - 1 Jan 1998

Sander T, Peters C, Janz D, Bianchi A, Bauer G, Wienker T F, Hildmann T, Epplen J T, Riess O

Abstract excerpt

Mutations in the gene encoding the alpha1A-calcium channel subunit play a causative role in the epileptogenesis of absence seizures in tottering mutant mice. The present family-based association and non-parametric linkage study tested the hypothesis that allelic variants of the homologous human gene (CACN1A4) confer susceptibility to common subtypes of idiopathic generalized epilepsy (IGE). An expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Calcium Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family Health

Share to Gene Frequency

Share to Genetic Linkage

Share to Polymorphism, Genetic

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 9477143
DOI: 10.1016/s0920-1211(97)00073-9

Genes

NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The gene encoding the alpha1A-voltage-dependent calcium channel (CACN1A4) is not a candidate for causing common subtypes of idiopathic generalized epilepsy.PMID 9477143Read ↗

Failure to replicate an allelic association between an exon 8 polymorphism of the human alpha(1A) calcium channel gene and common syndromes of idiopathic generalized epilepsy.Semantic proximity Read ↗

Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants.Semantic proximity Read ↗

No association between common variations in the human alpha 2 subunit gene (ATP1A2) of the sodium-potassium-transporting ATPase and idiopathic generalized epilepsy.Semantic proximity Read ↗

Possible association of a silent polymorphism in the neuronal nicotinic acetylcholine receptor subunit alpha4 with common idiopathic generalized epilepsies.Semantic proximity Read ↗

Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy.Semantic proximity Read ↗

Mutational analysis of CACNA1G in idiopathic generalized epilepsy. Mutation in brief #962. Online.Semantic proximity Read ↗

Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy.Semantic proximity Read ↗

Length variation of a polyglutamine array in the gene encoding a small-conductance, calcium-activated potassium channel (hKCa3) and susceptibility to idiopathic generalized epilepsy.Semantic proximity Read ↗

Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor alpha 1 and gamma 2 subunit gene cluster on chromosome 5.Semantic proximity Read ↗

T-type calcium channel gene alpha (1G) is not associated with childhood absence epilepsy in the Chinese Han population.Semantic proximity Read ↗

Linkage and association analysis of CACNG3 in childhood absence epilepsy.Semantic proximity Read ↗

Association between the alpha(1a) calcium channel gene CACNA1A and idiopathic generalized epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.