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Article

The voltage-gated sodium channel beta2-subunit gene and idiopathic generalized epilepsy.

Neuroreport - 21 Aug 2000

Haug K, Sander T, Hallmann K, Rau B, Dullinger J S, Elger C E, Propping P, Heils A

Abstract excerpt

Recent identification of ion channel gene mutations in Mendelian epilepsies suggests that genetically driven neuronal hyperexcitability plays an important role in epileptogenesis. In this study, we tested the hypothesis that genetic variation in the human SCN2B gene confers liability to common su...

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Share to Epilepsy, Generalized
Share to Gene Frequency
Share to Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myoclonic Epilepsy, Juvenile

Share to Nerve Tissue Proteins

Share to Polymorphism, Single-Stranded Conformational

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Share to Sodium Channels

Source

Identifiers

PMID: 10976944
DOI: 10.1097/00001756-200008210-00016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10976944-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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