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Article

[MELAS associated with diabetes mellitus and point mutation in mitochondrial DNA].

No to shinkei = Brain and nerve - 1 Mar 1992

Onishi H, Inoue K, Osaka H, Nagatomo H, Ando N, Yamada Y, Suzuki K, Hanihara T, Kawamoto S, Okuda K

Abstract excerpt

Point mutation of mitochondrial DNA has been described in the blood from a MELAS patient. The 39-year-old patient developed progressive dementia, stroke-like episodes, heart conduction defect (Lown-Ganong-Levin syndrome) and cortical blindness. CT scan revealed brain atrophy and low density areas in the bilateral occipital lobes. Laboratory tests showed hyperglycemia and lactic acidosis. Muscle biopsy showed...

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Share to Diabetes Mellitus, Type 1
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epilepsies, Myoclonic

Share to Mitochondria, Muscle

Share to Muscular Diseases

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Source

Identifiers

PMID: 1591103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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