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Article

Copy number amplification of 3q26–27 oncogenes in microdissected oral squamous cell carcinoma and oral brushed samples from areca chewers

19 May 2005

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is a worldwide disease. In South Asians, the high prevalence of OSCC is tightly linked to areca chewing. The prognosis for OSCC remains dismal and improvement in early diagnosis may benefit the survival of patients with this disease. Chromosome region 3q26-27 has been shown to carry several oncogenes. By quantitative PCR (Q-PCR), the gene copy numbers of TERC, PI3KCA, ZASC1,...

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PMID: 15906274
DOI: 10.1002/path.1790

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