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Genome‐wide profiling of oral squamous cell carcinoma

16 Sept 2004

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is a common malignancy, the incidence of which is particularly high in some Asian countries due to the geographically linked areca quid (AQ) chewing habit. In this study, array-based comparative genomic hybridization was used to screen microdissected OSCCs for genome-wide alterations. The highest frequencies of gene gain were detected for TP63, Serpine1, FGF4/FGF3, c-Myc and...

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PMID: 15372456
DOI: 10.1002/path.1640

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