Article
Cyclin D1 genotype in areca-associated oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 May 2003
Wong Yong-Kie, Lin Shu-Chun, Chang Che-Shoa, Tseng Yu-Hsin, Liu Chung-Ji, Lin Huey-Ching, Chang Kuo-Wei
Abstract excerpt
BACKGROUND: Oral squamous cell carcinoma (OSCC) is the most common malignancy in areca-chewing regions, accounting for up to 50% of malignant tumors in some South Asian countries. Amplification and/or over-expression of cyclin D1 (CCND1) is a frequent event in human malignancies, including OSCC. CCND1 G870A polymorphism (codon 242) gives rise to two isoforms of the protein. The objective of the present study was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
