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Methylenetetrahydrofolate reductase C677T polymorphism and Factor V Leiden variant in Mexican women with preeclampsia/eclampsia.

Blood cells, molecules & diseases - 1 Jan 2000

Dávalos I P, Moran M C, Martínez-Abundis E, González-Ortiz M, Flores-Martínez S E, Machorro V, Sandoval L, Figuera L E, Mena J P, Oliva J M, Tlacuilo-Parra J A, Sánchez-Corona J, Salazar-Páramo M

Abstract excerpt

The etiology of preeclampsia is still a matter of controversy. An association between hyperhomocysteinemia and preeclamptic patients has been described. A common missense mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased plasma homocysteine concentrations. In addition, the polymorphism of gene encoding for Factor V Leiden G1691A is associated with a prothrombotic state...

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Source

Identifiers

PMID: 15905108
DOI: 10.1016/j.bcmd.2005.03.008

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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