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Article

Genetic and cellular characterizations of human TCF4 with microsatellite instability in colon cancer and leukemia cell lines.

Cancer letters - 20 Feb 2006

Chang Huoy-Rou, Cheng Tian-Lu, Liu Tsan-Zon, Hu Han-Shu, Hsu Li-Sung, Tseng Wei-Chang, Chen Ching-Hsein, Tsao Der-An

Abstract excerpt

It has been reported that the mutational inactivation of the adenomatous polyposis coli (APC) and beta-catenin genes play important roles in colorectal carcinogenesis. However, alteration of the components in the Wnt signaling pathway in colorectal cancer (CRC) with microsatellite instability (MSI) has been elucidated. To define the precise role of the Wnt signaling components in CRC and leukemia cell lines with...

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Source

Identifiers

PMID: 15905022
DOI: 10.1016/j.canlet.2005.03.011

Genes

TCF4
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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