Article
[The investigation of gene-environment interaction using case-control comparisons].
Nederlands tijdschrift voor geneeskunde - 30 Apr 2005
Kellen E, Zeegers M P, Vandenbroucke J P, Buntinx F
Abstract excerpt
Many chronic diseases are caused by the interaction of genes and environmental factors. Genetic epidemiologic research seeks to elucidate the role of genetic factors and their interaction with environmental factors in the occurrence of disease. Gene-environment interaction can be assessed using different types of case-control comparisons. The classic case-control design is suitable to investigate the association...
Topics
- Case-Control Studies
- Environmental Exposure
- Epidemiologic Methods
- Genetic Predisposition to Disease
- Genotype
- Humans
- Models, Genetic
- Risk Factors
