Article
Association study of catechol-O-methyltransferase gene polymorphism in Korean male alcoholics.
Psychiatric genetics - 1 Jun 2005
Kweon Yong-Sil, Lee Hae Kook, Lee Chung Tai, Pae Chi-Un
Abstract excerpt
OBJECTIVE: Catechol-O-methyltransferase, which has a functional genetic polymorphism, plays an important role in dopamine metabolism. The study analyzed the association between the catechol-O-methyltransferase gene polymorphism and alcohol dependence in the Korean population. METHODS: Ninety-seven male alcoholics and 94 male age-matched normal controls were enrolled in this study. Polymerase chain reaction-based...
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