Article
Paternal age and intelligence: implications for age-related genomic changes in male germ cells.
Psychiatric genetics - 1 Jun 2005
Malaspina Dolores, Reichenberg Avi, Weiser Mark, Fennig Shmuel, Davidson Michael, Harlap Susan, Wolitzky Rachel, Rabinowitz Jonathan, Susser Ezra, Knobler Haim Y
Abstract excerpt
BACKGROUND: A robust association between advancing paternal age and schizophrenia risk is reported, and genetic changes in the germ cells of older men are presumed to underlie the effect. If that is so, then the pathway may include effects on cognition, as those with premorbid schizophrenia are reported to have lower intelligence. There are also substantial genetic influences on intelligence, so de novo genetic...
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