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Article

[Influence of paternal age in schizophrenia].

L'Encephale - 1 Jun 2011

Hubert A, Szöke A, Leboyer M, Schürhoff F

Abstract excerpt

BACKGROUND: Schizophrenia is an aetiologically heterogeneous syndrome, with a strong genetic component. Despite a reduced fertility in this disorder, its prevalence is maintained and could be explained by de novo genetic mutations. Advanced paternal age (APA) is a major source of new mutations in human beings and could thus be associated with an increased risk of developing schizophrenia in offspring. New...

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PMID: 21703435
DOI: 10.1016/j.encep.2010.12.005

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