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Article

Advancing paternal age and the risk of schizophrenia.

Archives of general psychiatry - 1 Apr 2001

Malaspina D, Harlap S, Fennig S, Heiman D, Nahon D, Feldman D, Susser E S

Abstract excerpt

BACKGROUND: A major source of new mutations in humans is the male germ line, with mutation rates monotonically increasing as father's age at conception advances, possibly because of accumulating replication errors in spermatogonial cell lines. METHOD: We investigated whether the risk of schizophrenia was associated with advancing paternal age in a population-based birth cohort of 87 907 individuals born in...

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Identifiers

PMID: 11296097
DOI: 10.1001/archpsyc.58.4.361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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