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Expression of multiple human endogenous retrovirus surface envelope proteins in ovarian cancer

29 Sept 2006

Abstract excerpt

Individual classes of human endogenous retrovirus (HERV) genes and proteins are expressed in cancer, but expression of more than one type of HERV is rare. We report here the expression of multiple HERV genes and proteins in ovarian cell lines and tissues. Expression of HERV-K env mRNA was greater in ovarian epithelial tumors than in normal ovarian tissues (N = 254). The expression of this protein on the surface...

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PMID: 17013901
DOI: 10.1002/ijc.22256

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