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Mean corpuscular volume and ADH1C genotype in white patients with alcohol-associated diseases.

Alcoholism, clinical and experimental research - 1 May 2005

Sun Leimin, König Inke R, Jacobs Arne, Seitz Helmut K, Junghanns Klaus, Wagner Thomas, Ludwig Diether, Jacrobs Arne, Homann Nils

Abstract excerpt

BACKGROUND: Alcohol abuse is associated with several gastrointestinal diseases, such as esophageal carcinoma, chronic alcoholic pancreatitis, and liver cirrhosis. Increased mean corpuscular volume (MCV) has been recognized as a biomarker for alcohol abuse and heavy drinkers. Recent studies from Japan revealed that macrocytosis is related to ALDH-2/2 genotype, leading to increased acetaldehyde accumulation. It has...

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PMID: 15897724
DOI: 10.1097/01.alc.0000163500.81691.74

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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