Article
Genotype of inflammatory cytokines in limbal stem cell graft in Italian patients.
Biochemical and biophysical research communications - 24 Jun 2005
Lescai Francesco, Conti Luigi, Bartolozzi Maurizio, Ramazzotti Giulia, Mazzi Marta, Sarnicola Vincenzo, Franceschi Claudio
Abstract excerpt
We tested the hypothesis that the genetic capability to mount an inflammatory response might contribute to the inter-individual variability of limbal stem cell graft (LSCG) outcome. Two functional polymorphisms in the IL-6 and TNF-alpha promoter regions were genotyped in 35 patients. A new score system (clinical assessment score, CAS) was set up in order to classify patients' clinical profile, and the main...
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