Article
Epithelioid gastrointestinal stromal tumor with PDGFRA activating mutation and immunoreactivity.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jun 2005
Yi Eunhee S, Strong Curtis R, Piao Zhe, Perucho Manuel, Weidner Noel
Abstract excerpt
The authors report a unique case of an intra-abdominal, epithelioid mesenchymal tumor that had an activating mutation of PDGFRA and a strong PDGFRA immunoreactivity but lacked both c-kit mutation and c-kit protein (CD117) expression. IHC study showed that the tumor cells were diffusely and strongly positive for PDGFRA, vimentin, CD34, and Bcl-2 but completely negative for CD117 as well as for muscle, epithelial,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.