Article
Relationship of bradykinin B2 receptor gene polymorphism with essential hypertension and left ventricular hypertrophy.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Dec 2004
Fu Yuxiao, Katsuya Tomohiro, Matsuo Akiko, Yamamoto Koichi, Akasaka Hiroshi, Takami Yoichi, Iwashima Yoshio, Sugimoto Ken, Ishikawa Kazuhiko, Ohishi Mitsuru, Rakugi Hiromi, Ogihara Toshio
Abstract excerpt
The bradykinin B2 receptor shows a protective role in the development of hypertension and renal and cardiovascular complications. It was recently reported that a polymorphism of the bradykinin B2 receptor gene (BDKRB2) is a genetic predisposing factor for hypertension and cardiovascular disease. The aim of this study was to examine the relationship of a polymorphism (-58 T/C and exon 1 +9/-9) of BDKRB2, and an...
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