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Article

Muscle strength response to strength training is influenced by insulin-like growth factor 1 genotype in older adults.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jun 2005

Kostek Matthew C, Delmonico Matthew J, Reichel Jonathan B, Roth Stephen M, Douglass Larry, Ferrell Robert E, Hurley Ben F

Abstract excerpt

Strength training (ST) is considered an intervention of choice for the prevention and treatment of sarcopenia. Reports in the literature have suggested that the insulin-like growth factor I protein (IGF-I) plays a major role in ST-induced skeletal muscle hypertrophy and strength improvements. A microsatellite repeat in the promoter region of the IGF1 gene has been associated with IGF-I blood levels and phenotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15894537
DOI: 10.1152/japplphysiol.00817.2004

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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