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Article

Influence of promoter region variants of insulin-like growth factor pathway genes on the strength-training response of muscle phenotypes in older adults.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Nov 2007

Hand Brian D, Kostek Matthew C, Ferrell Robert E, Delmonico Matthew J, Douglass Larry W, Roth Stephen M, Hagberg James M, Hurley Ben F

Abstract excerpt

To examine the influence of insulin-like growth factor (IGF) pathway gene polymorphisms on muscle mass and strength responses to strength training (ST), we studied 128 White and Black men and women before and after a 10-wk single-leg knee extension ST program. One-repetition maximum strength, muscle volume (MV) via computed tomography, and muscle quality (MQ) were assessed at baseline and after 10 wk of ST. There...

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Identifiers

PMID: 17761791
DOI: 10.1152/japplphysiol.00420.2007
PMCID: PMC2811278

Genes

IGF1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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