Article
Common genetic variation in the IGF1 associates with maximal force output.
Medicine and science in sports and exercise - 1 Dec 2011
Huuskonen Antti, Lappalainen Jani, Oksala Niku, Santtila Matti, Häkkinen Keijo, Kyröläinen Heikki, Atalay Mustafa
Abstract excerpt
PURPOSE: We clarified the effect of insulin-like growth factor-1 (IGF1), IGF-binding protein-3 (IGFBP3), interleukin-6 (IL6), and its receptor (IL6R) gene variants on muscular and aerobic performance, body composition, and on circulating levels of IGF-1 and IL-6. Single nucleotide polymorphisms (SNPs) may, in general, influence gene regulation or its expression, or the structure and function of the corresponding...
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