Article
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation.
Cellular signalling - 1 Aug 2005
Tawadros Thomas, Martin David, Abderrahmani Amar, Leisinger Hans-Jürg, Waeber Gérard, Haefliger Jacques-Antoine
Abstract excerpt
The scaffold protein Islet-Brain1/c-Jun amino-terminal kinase Interacting Protein-1 (IB1/JIP-1) is a modulator of the c-Jun N-terminal kinase (JNK) activity, which has been implicated in pleiotrophic cellular functions including cell differentiation, division, and death. In this study, we described the presence of IB1/JIP-1 in epithelium of the rat prostate as well as in the human prostatic LNCaP cells. We...
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