Article
Genetic factors contribute to bleeding after cardiac surgery.
Journal of thrombosis and haemostasis : JTH - 1 Jun 2005
Welsby I J, Podgoreanu M V, Phillips-Bute B, Mathew J P, Smith P K, Newman M F, Schwinn D A, Stafford-Smith M
Abstract excerpt
BACKGROUND: Postoperative bleeding remains a common, serious problem for cardiac surgery patients, with striking inter-patient variability poorly explained by clinical, procedural, and biological markers. OBJECTIVE: We tested the hypothesis that genetic polymorphisms of coagulation proteins and platelet glycoproteins are associated with bleeding after cardiac surgery. PATIENTS/METHODS: Seven hundred and eighty...
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