Article
Novel, mechanism-based therapies for cystic fibrosis.
Current opinion in pediatrics - 1 Jun 2005
Rubenstein Ronald C
Abstract excerpt
PURPOSE OF REVIEW: Cystic fibrosis results from disruption of the biosynthesis or function of the cystic fibrosis transmembrane conductance regulator. Cystic fibrosis transmembrane conductance regulator plays a critical role in the regulation of epithelial ion transport. Restoration of cystic fibrosis transmembrane conductance regulator function should improve the cystic fibrosis phenotype. RECENT FINDINGS:...
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