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Article

Diversifying selection in human papillomavirus type 16 lineages based on complete genome analyses.

Journal of virology - 1 Jun 2005

Chen Zigui, Terai Masanori, Fu Leiping, Herrero Rolando, DeSalle Rob, Burk Robert D

Abstract excerpt

Human papillomavirus type 16 (HPV16) is the primary etiological agent of cervical cancer, the second most common cancer in women worldwide. Complete genomes of 12 isolates representing the major lineages of HPV16 were cloned and sequenced from cervicovaginal cells. The sequence variations within the open reading frames (ORFs) and noncoding regions were identified and compared with the HPV16R reference sequence....

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Identifiers

PMID: 15890941
DOI: 10.1128/JVI.79.11.7014-7023.2005
PMCID: PMC1112126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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