Article
G20210A prothrombin mutation and critical limb ischaemia in patients with peripheral arterial disease.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Jul 2009
Sartori M, Favaretto E, Legnani C, Cini M, Conti E, Pili C, Palareti G
Abstract excerpt
OBJECTIVES: To assess the possible association between inherited thrombophilic alterations and the severity of peripheral arterial disease (PAD). DESIGN: A case-control study. METHODS: We evaluated the presence of G20210A prothrombin (FII) and R506Q FV Leiden mutations, antithrombin, protein C and S deficiencies in 176 patients with PAD at Fontaine's stage II and in 106 patients with critical limb ischaemia...
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