Article
Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 2005
Leung Wing, Iyengar Rekha, Triplett Brandon, Turner Victoria, Behm Frederick G, Holladay Marti S, Houston James, Handgretinger Rupert
Abstract excerpt
The repertoire of killer Ig-like receptors (KIRs) can be determined at the level of DNA, RNA, or surface protein expression for selection of blood stem cell donors. We compared genotyping and phenotyping of the four inhibitory KIRs that are important in transplantation for leukemia in 73 unrelated persons. In 5 (7%) of the 68 individuals in whom the KIR2DL1 gene was present and in 10 (15%) of the 67 in whom...
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