Article
Optimization of a genotypic assay applicable to all human immunodeficiency virus type 1 protease and reverse transcriptase subtypes.
Journal of virological methods - 1 Sept 2005
Snoeck J, Riva C, Steegen K, Schrooten Y, Maes B, Vergne L, Van Laethem K, Peeters M, Vandamme A-M
Abstract excerpt
Genotypic assays are used often to guide clinicians in decisions concerning the treatment of patients. An optimized sequence-based genotypic assay was used to determine the whole protease and reverse transcriptase (RT) gene, including the gag cleavage site region and RNase H region. Since non-B subtypes are increasing in countries where subtype B was the most prevalent subtype, and treatment becomes more...
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