Article
A biochemical and structural analysis of genetic diversity within the HLA-A*11 subtype.
Immunogenetics - 1 Jun 2005
Li Lenong, Chen Weifeng, Bouvier Marlene
Abstract excerpt
The HLA-A*11 subtype includes 17 naturally occurring variants (-A*1101 to -A*1117) distributed among different ethnic groups worldwide. At present, only HLA-A*1101 has been characterized at the molecular, structural, and immunological level. Developing similar knowledge on other HLA-A*11 alleles is highly important for bone marrow and graft transplantation. This is also important to better understand disease...
Topics
- Binding Sites
- Genetic Variation
- HLA-A Antigens
- Humans
- Peptide Fragments
- Protein Structure, Tertiary
- Temperature
