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Article

Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations.

AIDS (London, England) - 20 May 2005

Crothers Kristina, Beard Charles B, Turner Joan, Groner Gena, Fox Melissa, Morris Alison, Eiser Shary, Huang Laurence

Abstract excerpt

BACKGROUND: The impact of Pneumocystis jirovecii (formerly P. carinii) dihydropteroate synthase (DHPS) gene mutations on morbidity and mortality of Pneumocystis pneumonia (PCP) in HIV-positive patients is unclear. OBJECTIVE: To determine whether severity and outcome of HIV-associated PCP differs according to DHPS genotype. SETTING: A prospective, observational study in a university-affiliated county hospital....

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Identifiers

PMID: 15867494
DOI: 10.1097/01.aids.0000168974.67090.70

Genes

DHPS

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